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1 News 502 Publications 18 Members

Crosstalk between the ubiquitin and SUMO pathways

Huaiyu Sun Tony Hunter

Tony Hunter: kinase king. Interview by Ruth Williams.

T, Hunter

Published in The Journal of Cell Biology

Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote s-phase genome stabil...

Bailis, Julie M Luche, Douglas D Hunter, Tony Forsburg, Susan L

Published in Molecular and cellular biology

The minichromosome maintenance (MCM) complex plays essential, conserved roles throughout DNA synthesis: first, as a component of the prereplication complex at origins and, then, as a helicase associated with replication forks. Here we use fission yeast (Schizosaccharomyces pombe) as a model to demonstrate a role for the MCM complex in protecting re...

Instructive role of aPKCz subcellular localization in the assembly of adherens junctions in neural progenitors

Ghosh, S Marquardt, T Thaler, J P Carter, N Andrews, S E Pfaff, S L Tony Hunter

Crosstalk between the SUMO and ubiquitin pathways

Tony Hunter Huaiyu Sun

Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells.

Gw, Pearson T, Hunter

Published in The Journal of Cell Biology

To determine how extracellular signal-regulated kinases (ERK) 1/2 promote mammary tumorigenesis, we examined the real-time behavior of cells in an organotypic culture of the mammary glandular epithelium. Inducible activation of ERK1/2 in mature acini elicits cell motility and disrupts epithelial architecture in a manner that is reminiscent of ducta...

A not so brief history of the Oncogene Meeting and its cartoons

Tony Hunter Simon, J

Published in Oncogene

Akt inhibitor A-443654 induces rapid Akt Ser-473 feedback phosphorylation independent of mTORC1 inhibition

Han, E K Leverson, J D Mcgonigal, T Shah, O J Woods, K W Tony Hunter Giranda, V L Luo, Y

Published in Oncogene

Essential role of Tuberous Sclerosis Complex genes TSC1/2 in NF-B activation and cell survival

Ghosh, S Tergaonkar, V Rothlin, C V Correa, R C Bottero, V Bist, P Verma, I M Tony Hunter

Published in Cancer Cell International

MEKK1: dual function as a protein kinase and a ubiquitin protein ligase

Lu, Z Tony Hunter

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