Phosphorylation and spindle pole body localization of the Cdc15p mitotic regulatory protein kinase in budding yeast
Published in Current Biology
Published in Current Biology
Published in Current Biology
Tuberous sclerosis is a largely benign tumor syndrome derived from the acquisition of somatic lesions in genes encoding the tumor suppressor products, TSC1 or TSC2. Loss of function of the TSC1-TSC2 complex, which acts as a Rheb GAP, yields constitutive, unrestrained signaling from the cell growth machinery comprised of Rheb, mTOR, and S6K. We demo...
Published in Current Biology
Published in Current Biology
Published in Current Biology
Published in Current Biology
Published in Current Biology
Published in Current Biology
Published in Current Biology