The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
Published in PloS one
Three p160 family members, p/CIP, SRC1, and TIF2, have been identified as transcriptional coactivators for nuclear hormone receptors and other transcription factors in vitro. In a previous study, we reported initial characterization of the obesity-resistant phenotypes of p/CIP and SRC-1 double knockout (DKO) mice, which exhibit increased energy exp...
