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Discovering the first tyrosine kinase.

Hunter, Tony

Published in Proceedings of the National Academy of Sciences of the United States of America

In the middle of the 20th century, animal tumor viruses were heralded as possible models for understanding human cancer. By the mid-1970s, the molecular basis by which tumor viruses transform cells into a malignant state was beginning to emerge as the first viral genomic sequences were reported and the proteins encoded by their transforming genes w...

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